A warrior named Kenshiro, the successor of a deadly martial art style known as Hokuto Shinken, which gives him the ability to kill most adversaries from within through the use of the human body's secret vital points, often resulting in an exceptionally violent and gory death. Kenshiro dedicates his life to fighting against the various ravagers who threaten the lives of the weak and innocent, as well as rival martial artists. This time he saves the earth from a gigantic demon witch and her arm of fighters.