In 1916, Chu Shaohua marries Chen Dashun, the eldest son of the Chen family’s pharmacy, to save her brother. With integrity and sharp business skills, she earns the respect of Chen’s father and becomes the manager. After the sudden deaths of Chen’s father and Dashun, the pharmacy passes to Chen Ershun, who squanders the family fortune, driving it to ruin. Through hardship, Chu Shaohua establishes Huashun Pharmacy to support the family. Just as she plans to start a new life with her first love, Xia Chu, Chen Ershun and his mother block her path. When bandits raid the Chen household, Chu loses her daughter and, devastated, leaves for Shanghai. There, her outstanding performance at Yongxin Department Store draws the attention of business talent Wen Zhiqiu, who invites her to co-found a new venture. Step by step, she rises to become a bold and trustworthy woman entrepreneur.